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Which statement regarding tuberculosis (TB) is correct?

  1. Meningitis is the leading cause of death from tuberculosis.

  2. Chemotherapy could eradicate the disease if widely available.

  3. Many TB cases are associated with HIV.

  4. The TB bacillus is difficult to isolate.

The correct answer is: Many TB cases are associated with HIV.

The statement that many TB cases are associated with HIV is correct because individuals with HIV have a compromised immune system, which increases their susceptibility to tuberculosis. In fact, HIV is a significant co-infection among TB patients, as it accelerates the progression of latent TB infection to active TB disease. The World Health Organization (WHO) has highlighted the nexus between TB and HIV, emphasizing the need for integrated approaches to diagnosis and treatment for both infections, particularly in regions where both are prevalent. Understanding the relationship between TB and HIV is crucial for public health planning and intervention strategies, as it helps prioritize screening and treatment efforts targeted at high-risk populations. Globally, HIV is one of the most significant risk factors for progression to TB among those infected with Mycobacterium tuberculosis, making this knowledge vital for effective public health nursing practice.